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The lawsuit filed by Tina Herford claimed that she developed mesothelioma after using J&J talcum powder products that her lawyers claimed contained asbestos.
The August trial was underpinned by errors and insufficient evidence on both sides, culminating in excessive damages, the judge said.
$417 million is the largest sum awarded in a series of talcum powder lawsuit verdicts against Johnson & Johnson in courts around the US.
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