Knee osteoarthritis News

"Almost all patients with primary knee OA experience periods of warmth and swelling in the joint, with increases in pain and reduction of function," said the study co-author. Male and female patients with primary knee OA who had swelling and pain in both knee joints for at least six months, and also had evidence of OA on their X-rays, were recruited for the study. Patients with signs of local inflammation, such as pain and swelling of the whole knee with warmth, were checked.

Researchers believe bisphosphonates may alter bone marrow lesions, and thereby could improve pain in OA and halt its progression Alternatively, they could also alter the mechanical properties of bone, thereby potentially contributing to detrimental effects Measurements in bone marrow lesion volume were taken when they first started on bisphosphonate and then a year later